The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors (CBRs), and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system (including the brain) and …
What are the components of the endocannabinoid system?
The endocannabinoid system consists of three main components:
- A widespread network of cannabinoid receptors throughout the body including cannabinoid receptor type 1 and type 2 (CB1 and CB2)
- Endogenous cannabinoids or endocannabinoids (eCBs) such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG)
How do you make endocannabinoids?
Endocannabinoids are produced from arachidonic acid, an omega-6 fatty acid.
Sources of endocannabinoid-enhancing fatty acids:
- Hemp seeds and hemp oil.
- Flax seeds (grind at home in a coffee grinder) and flax oil.
- Chia seeds.
- Sardines and anchovies.
- Eggs (pasture-fed or omega-3 enriched only)
Where are endocannabinoids made?
Endocannabinoids are molecules that, like the plant cannabinoid THC, bind to and activate cannabinoid receptors. However, unlike THC, endocannabinoids are produced naturally by cells in the human body (“endo” means “within,” as in within the body).
How do you explain the endocannabinoid system?
The endocannabinoid system, with its complex actions in our immune system, nervous system, and all of the body’s organs, is literally a bridge between body and mind. By understanding this system we begin to see a mechanism that explains how states of consciousness can promote health or disease.
Which chemical is an endocannabinoid?
Humans and animals alike naturally synthesize endocannabinoids, chemical compounds that activate the same receptors as delta-9-tetrahydrocannabinol (THC), the active component of marijuana (Cannabis sativa).
How does endocannabinoids affect the brain?
The endocannabinoid system (ECS) in the brain primarily influences neuronal synaptic communication, and affects biological functions—including eating, anxiety, learning and memory, reproduction, metabolism, growth and development—via an array of actions throughout the nervous system.
Why do humans have endocannabinoid system?
The endocannabinoid system is a molecular system responsible for regulating and balancing many processes in the body, including immune response, communication between cells, appetite and metabolism, memory, and more.
Does everyone have an endocannabinoid system?
The answer is the endocannabinoid system. It is present nearly everywhere in the human body and functions by maintaining the homeostasis of the human body (Alger, 2013).