Ephedrine Sulfate Injection, USP is indicated in the treatment of allergic disorders, such as bronchial asthma. The drug has long been used as a pressor agent, particularly during spinal anesthesia when hypotension frequently occurs.
What is Ephedrine used for?
Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.
Is ephedrine sulfate the same as ephedrine?
The major difference between the two medications is in the bronchodilator active ingredient. While Bronkaid contains ephedrine sulfate as its active ingredient, Primatene contains ephedrine HCl. They also contain different amounts of each active ingredient.
How does ephedrine affect the body?
Because of its direct sympathomimetic effects, ephedrine can increase heart rate, contractility, cardiac output, and peripheral resistance. Thus, increases in both heart rate and blood pressure are common observations after ephedrine ingestion.
What is ephedrine used to make?
Ephedrine is a medication and stimulant. It is often used to prevent low blood pressure during spinal anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment.
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|CAS Number||299-42-3 as salt: 2134-72-5|
When is ephedrine given?
EPHEDRINE (e FED rin) injection is used to treat low blood pressure in patients who received certain types of anesthesia, underwent a specific type of surgery, or received an overdose of a drug that can lower blood pressure.
Who should avoid taking ephedrine?
high blood pressure. diminished blood flow through arteries of the heart. coronary artery disease. a low supply of oxygen rich blood to the heart.
Does ephedrine increase dopamine?
Ephedrine, which has been used as a decongestant and weight loss agent, causes both central serotonin and dopamine (DA) release (Bowyer et al., 2000).
Why is ephedrine controlled?
Stringent regulation of all ephedrine products is necessary to prevent misuse and to protect the public’s health.
Is ephedrine available over-the-counter?
Ephedrine is available over-the-counter (OTC) as an oral medication in combination with the expectorant guaifenesin, and comes in the form of tablets, caplets, or syrup. It is not a replacement for prescription asthma treatments.
Does ephedrine cause liver damage?
The severity of liver injury due to ephedrine ranges from mild, asymptomatic elevations in serum enzymes to clinically apparent acute liver injury and to acute liver failure.
Is ephedrine basic or acidic?
It has a role as a nasal decongestant, a sympathomimetic agent, a vasoconstrictor agent, a xenobiotic, an environmental contaminant, a plant metabolite and a bacterial metabolite. It is a member of phenylethanolamines and a phenethylamine alkaloid. It is a conjugate base of a (-)-ephedrinium.
When was ephedrine banned?
The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedrine alkaloids (stimulant compounds found in Ephedra sinica and some other plants) in the United States in 2004.
Does ephedrine damage your heart?
Ephedra can cause severe life-threatening or disabling conditions in some people. Ephedra use is linked to high blood pressure, heart attacks, muscle disorders, seizures, strokes, irregular heartbeat, loss of consciousness, and death.
Which is better ephedrine or pseudoephedrine?
Ephedrine applied to the nasal mucosa reduces nasal resistance more quickly and strongly than oral pseudoephedrine, but with shorter action time , . At end of treatment, there may be a rebound effect with increased nasal resistance and recurrence of congestion, for which several hypotheses have been suggested.
What is the structure of ephedrine?