What Is Ephedrine? Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.
What does ephedrine do to the body?
Because of its direct sympathomimetic effects, ephedrine can increase heart rate, contractility, cardiac output, and peripheral resistance. Thus, increases in both heart rate and blood pressure are common observations after ephedrine ingestion.
What type of drug is ephedrine?
Ephedrine is a prescription medicine used to treat the symptoms of low blood pressure during anesthesia (Hypotension). Ephedrine may be used alone or with other medications. Ephedrine belongs to a class of drugs called Alpha/Beta Adrenergic Agonists.
Is Ephedrine HCl the same as ephedrine?
The major difference between the two medications is in the bronchodilator active ingredient. While Bronkaid contains ephedrine sulfate as its active ingredient, Primatene contains ephedrine HCl. They also contain different amounts of each active ingredient.
Is ephedrine hydrochloride legal?
For example, ephedrine was a main ingredient in a product called Herbal Ecstasy, which was promoted as a legal and healthier alternative to MDMA (ecstasy). In 2004, the Federal Drug Administration (FDA) banned ephedrine from dietary supplements as it was deemed an unreasonable risk to public health.
What are the long term effects of ephedrine?
Ephedra can cause severe life-threatening or disabling conditions in some people. Ephedra use is linked to high blood pressure, heart attacks, muscle disorders, seizures, strokes, irregular heartbeat, loss of consciousness, and death.
Does ephedrine cause liver damage?
The severity of liver injury due to ephedrine ranges from mild, asymptomatic elevations in serum enzymes to clinically apparent acute liver injury and to acute liver failure.
Which is better ephedrine or pseudoephedrine?
Ephedrine applied to the nasal mucosa reduces nasal resistance more quickly and strongly than oral pseudoephedrine, but with shorter action time , . At end of treatment, there may be a rebound effect with increased nasal resistance and recurrence of congestion, for which several hypotheses have been suggested.
What is another name for ephedrine?
Ephedrine is available under the following different brand names: Akovaz, and Corphedra.
Is ephedrine basic or acidic?
It has a role as a nasal decongestant, a sympathomimetic agent, a vasoconstrictor agent, a xenobiotic, an environmental contaminant, a plant metabolite and a bacterial metabolite. It is a member of phenylethanolamines and a phenethylamine alkaloid. It is a conjugate base of a (-)-ephedrinium.
Why is ephedrine controlled?
Stringent regulation of all ephedrine products is necessary to prevent misuse and to protect the public’s health.
Is ephedrine available over-the-counter?
Ephedrine is available over-the-counter (OTC) as an oral medication in combination with the expectorant guaifenesin, and comes in the form of tablets, caplets, or syrup. It is not a replacement for prescription asthma treatments.
Does Bronkaid contain ephedrine?
Bronkaid Caplets contain 25 mg of ephedrine and 400 mg of guaifenesin per caplet, so the usage danger point is different: more than 6 caplets in 24 hours or more than 4 caplets in 24 hours for 3 or more days per week. Both products warn patients that they will not give relief as quickly as an inhaled bronchodilator.
Is Ephedrine HCL legal in USA?
Dietary supplements containing ephedrine are illegal in the United States, with the exception of those used in traditional Chinese medicine, where its presence is noted by má huáng.
When was ephedrine banned?
The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedrine alkaloids (stimulant compounds found in Ephedra sinica and some other plants) in the United States in 2004.
What is the structure of ephedrine?