In severe toxic doses it can cause coma, hypotension, multiple seizures, QRS widening, QTc prolongation, status epilepticus, and ventricular dysrhythmias . Seizure due to intentional or unintentional overdose is among the most commonly reported toxic effect of bupropion [3–6].
What are the side effects of taking too much Wellbutrin?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Wellbutrin XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.
How much Wellbutrin is too much?
Maximum dosage: 450 mg per day, taken in divided doses of no more than 150 mg each. Your doctor may prescribe this dosage for you if you don’t respond to several weeks of treatment.
What does a wellbutrin overdose feel like?
After an overdose of bupropion, clinical effects are primarily on the neurological, cardiovascular and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucination, coma, and seizures.
What happens if you accidentally take an extra Wellbutrin?
Do not take more than your prescribed dose since higher doses may increase your risk of having a seizure. Since quickly increasing the dose of bupropion can cause seizures in some people, your doctor will slowly increase your dose.
Does Wellbutrin make you hypersexual?
A small double-blind study by Clayton et al. reported that bupropion, compared to placebo, increases the desire to engage in sexual activity and frequency of engaging in sexual activity [12-14]. A similar report by Borge et al. shows an increased libido as a bupropion side effect .
Is 150 mg of bupropion a lot?
Adults—At first, 100 milligrams (mg) two times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg three times per day, taken at least 6 hours apart.
Does Wellbutrin make you horny?
I’d say that Wellbutrin has made my libido higher than its baseline. It gives me a little energy and motivation but is in no way like a traditional stimulant. I find it less effective on depression and anxiety than the SSRI’s But I still prefer it due to the lack of sexual side effects and the motivation boost.
What can you not mix with Wellbutrin?
Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Do not take bupropion to treat more than one condition at a time.
What happens if you take 600 mg of bupropion?
In mild to moderate toxic doses it produces agitation, hallucination, tachycardia, tremor, and single episodes of seizure. In severe toxic doses it can cause coma, hypotension, multiple seizures, QRS widening, QTc prolongation, status epilepticus, and ventricular dysrhythmias .
How likely is a seizure on Wellbutrin?
Seizures: Bupropion is associated with seizures in approximately 0.4% (4/1,000) of patients treated at doses up to 450 mg/day. This incidence of seizures may exceed that of other marketed antidepressants by as much as 4-fold.
What happens if you take 300 mg of bupropion?
300 mg/day of bupropion HCl sustained-release: anorexia, dry mouth, rash, sweating, tinnitus, and tremor. 400 mg/day of bupropion HCl sustained-release: abdominal pain, agitation, anxiety, dizziness, dry mouth, insomnia, myalgia, nausea, palpitation, pharyngitis, sweating, tinnitus, and urinary frequency.
Does Wellbutrin give you energy like Adderall?
Are Wellbutrin and Adderall the same? No. Wellbutrin is an antidepressant, and Adderall is a stimulant. They have differences in dosing, pricing, side effects, and drug interactions.
How do you treat Wellbutrin overdose?
Management of bupropion overdose is largely supportive
Treatment with activated charcoal should be considered for patients presenting within 60 minutes of ingestion in whom the risk of aspiration is low. Whole bowel irrigation may be considered for patients with large ingestions of sustained-release preparations.
How long does it take for wellbutrin to get out of your system?
The half-life of any medication is the amount of time it stays in your system when it hits half of its effectiveness. At between 33 to 37 hours, the half-life of Wellbutrin is exceptionally long for an antidepressant.
How much weight can I lose with Wellbutrin?
Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more.