How many classes of antidepressants are there?
There are five major classes of antidepressant and several others that are less commonly used. Each has its own benefits, risks, and appropriate uses. While some may be considered preferred options, the drug selection can vary based on your symptoms, history of treatment, and co-existing psychological disorders.
What are the four main classes of antidepressants?
Antidepressants can be divided into four major classes which include:
- Tricyclic antidepressants.
- Monoamine oxidase inhibitors (MAOIs)
- Serotonin reuptake inhibitors (SSRIs)
- Atypical antidepressants.
Which class of antidepressants is most effective?
Selective serotonin reuptake inhibitors (SSRIs) are the most effective class of antidepressants. Tricyclic antidepressants (TCAs) are the most effective class of antidepressants.
What is the best antidepressant with the least side effects?
Antidepressants with the lowest rate of sexual side effects include:
- Bupropion (Wellbutrin XL, Wellbutrin SR)
- Mirtazapine (Remeron)
- Vilazodone (Viibryd)
- Vortioxetine (Trintellix)
Which antidepressant is best for anxiety?
The antidepressants most widely prescribed for anxiety are SSRIs such as Prozac, Zoloft, Paxil, Lexapro, and Celexa. SSRIs have been used to treat generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and post-traumatic stress disorder.
What is the strongest antidepressant?
The most effective antidepressant compared to placebo was the tricyclic antidepressant amitriptyline, which increased the chances of treatment response more than two-fold (odds ratio [OR] 2.13, 95% credible interval [CrI] 1.89 to 2.41).
What is the #1 antidepressant?
Zoloft is the most commonly prescribed antidepressant; nearly 17% of those survey in the 2017 antidepressant use study reported that they had taken this medication. 1
Which antidepressant is best for weight loss?
“We found that bupropion is the only antidepressant that tends to be linked to weight loss over 2 years,” study leader David Arterburn, MD, Group Health Research Institute, Seattle, Washington, said in a Group Health Research Institute news release.
What is the oldest antidepressant?
The 1950s saw the clinical introduction of the first two specifically antidepressant drugs: iproniazid, a monoamine-oxidase inhibitor that had been used in the treatment of tuberculosis, and imipramine, the first drug in the tricyclic antidepressant family.
Are tricyclics better than SSRIs?
Conclusions: Overall efficacy between the two classes is comparable but SSRIs are not proven to be as effective as TCAs in in-patients and against amitriptyline. SSRIs have a modest advantage in terms of tolerability against most TCAs.
Are antidepressants bad for you?
The range of their uses has expanded from depression to anxiety, obsessive-compulsive disorder, eating disorders, and many other psychiatric conditions. These types of antidepressants are generally safe, but no medical treatment is without risk.
What happens if you drink alcohol while taking antidepressants?
Drinking alcohol while taking antidepressants is generally not advised because alcohol can make depression worse. It can also increase the side effects of some antidepressants, such as drowsiness, dizziness and co-ordination problems.
What can I take instead of antidepressants?
Several treatments can be used instead of antidepressants for treating depression and other mental health conditions.
- Talking therapies. Cognitive behavioural therapy. …
- Exercise. …
- Self-help groups. …
- Lithium. …
- Electric shock treatment.
Which antidepressant has the most side effects?
Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.