Is ephedrine acidic or basic?

Also, a salt such as ephedrine hydrochloride can be prepared between a weak base-ephedrine and a strong acid-hydrochloric acid. Third, the combination of a weak base-codeine and a weak acid-phosphoric acid can be used, as in codeine phosphate.

Is Ephedrine a base?

It is a member of phenylethanolamines and a phenethylamine alkaloid. It is a conjugate base of a (-)-ephedrinium. Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].

What class is ephedrine?

Ephedrine belongs to a class of drugs called Alpha/Beta Adrenergic Agonists.

Is ephedrine hydrochloride acidic or basic?

Structure for Ephedrine hydrochloride (DBSALT001513)

Property Value Source
logS -1.3 ALOGPS
pKa (Strongest Acidic) 13.89 ChemAxon
pKa (Strongest Basic) 9.52 ChemAxon
Physiological Charge 1 ChemAxon

Is Ephedrine a salt?

Chemically, it is an alkaloid with a phenethylamine skeleton found in various plants in the genus Ephedra (family Ephedraceae). It works mainly by increasing the activity of norepinephrine (noradrenaline) on adrenergic receptors. It is most usually marketed as the hydrochloride or sulfate salt.

Is Ephedrine a weak acid?

Because many drugs are either weak acids or weak bases and have limited water solubility, they are often used as their “salts” to increase their aqueous solubility. … Also, a salt such as ephedrine hydrochloride can be prepared between a weak base-ephedrine and a strong acid-hydrochloric acid.

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What products contain ephedrine?

Product(s) containing ephedrine:

  • ephedrine systemic. …
  • ephedrine nasal. …
  • aminophylline/amobarbital/ephedrine systemic. …
  • aminophylline/ephedrine/guaifenesin/phenobarbital systemic. …
  • aminophylline/ephedrine/phenobarbital/potassium iodide systemic.

What is another name for ephedrine?

Ephedrine is available under the following different brand names: Akovaz, and Corphedra.

Which is better ephedrine or pseudoephedrine?

Ephedrine applied to the nasal mucosa reduces nasal resistance more quickly and strongly than oral pseudoephedrine, but with shorter action time [10], [11]. At end of treatment, there may be a rebound effect with increased nasal resistance and recurrence of congestion, for which several hypotheses have been suggested.

What is ephedrine for?

What Is Ephedrine? Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.

Why is ephedrine controlled?

Stringent regulation of all ephedrine products is necessary to prevent misuse and to protect the public’s health.

When was ephedrine banned?

The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedrine alkaloids (stimulant compounds found in Ephedra sinica and some other plants) in the United States in 2004.

What is the chemical structure of ephedrine?

C10H15NO

How long does ephedrine stay in your system?

Approximate Detection Times

Amphetamine-Type Stimulants LOQ (ng/mL) Detection Time* up to
3,4‑Methylenedioxyamphetamine (MDA) 25 2 days
3,4‑Methylenedioxymethamphetamine (MDMA) 25 2 days
Phentermine 25
Ephedrine/pseudoephedrine 25 5 days

What color is ephedrine?

2.1. Ephedrine reacts with the expected blue colour, but the intensity of the colour is weak as compared to methamphetamine and to other secondary amines such as piperidine. The full development of the colour requires 5 to 10 minutes.

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Health Canada has authorized the use of ephedrine only in nasal decongestants and it does not permit the sale of products: 1. Containing more than 8 milligrams per dose; 2. That recommend the use of more than 32 milligrams of ephedrine a day; 3.

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