Depakote (divalproex sodium) and Abilify (aripiprazole) are used to treat manic episodes associated with bipolar disorder. Depakote is also used to treat epilepsy and migraine headaches. Abilify is also used to treat schizophrenia, depression, autistic disorder, and some irritable behavior disorders.
Does Depakote help bipolar depression?
Very little research has been conducted with bipolar disorder, and no medications have an FDA indication to treat bipolar depression. Previous studies suggest that Depakote is promising in the treatment of mixed and depressed episodes of bipolar disorder.
Can Depakote worsen depression?
Antiepileptic drugs (AEDs), including Depakote, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Tell your doctor if you have new or worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.
Does Depakote help with anxiety?
Valproic Acid (Depakote)
Valproic acid is an epilepsy medication that is now used for the treatment of panic attacks as well as other psychiatric problems. May work better by adding it to a primary medication that is not completely effective. Possible Disadvantages.
Does Depakote improve mood?
Anticonvulsants are sometimes taken to treat the manic episodes associated with bipolar disorder. Depakote is sometimes prescribed when patients experience rapid cycling of mood episodes and works by calming the hyperactivity of the brain during mania.
Is 500mg of Depakote a lot?
Depakote ER is indicated for prophylaxis of migraine headaches in adults. The recommended starting dose is 500 mg once daily for 1 week, thereafter increasing to 1000 mg once daily.
Does Depakote work right away?
Tablets take 4 hours to reach a peak, Depakote sprinkles take just over three. Food can delay the absorption of Depakote (food has a more significant effect on the tablets compared with the sprinkles). It may take several weeks of regular dosing before an effect on mood or seizure frequency is reported.
Does Depakote make you feel weird?
In Summary. Common side effects of Depakote include: abdominal pain, asthenia, dizziness, drowsiness, nausea, and anorexia. Other side effects include: abnormality in thinking, alopecia, ataxia, nystagmus disorder, tremor, weight loss, fever, and skin rash.
What are signs of Depakote toxicity?
CNS findings in cases of VPA overdose may include the following:
- Worsened seizure control.
Does everyone gain weight on Depakote?
Mood stabilizers used to treat bipolar disorder include lithium (Lithobid), valproic acid (Depakene), divalproex sodium (Depakote), carbamazepine (Tegretol, Equetro, others) and lamotrigine (Lamictal). All of these medications are known to increase the risk of weight gain except lamotrigine.
Does Depakote help anger?
Valproic Acid/Depakote® may be helpful for decreasing severe anger and mood lability, that does not respond to antidepressants.
Does Depakote make you sleep?
Q: What are the most common side effects experienced with Depakote? A: Common side effects experienced with Depakote include drowsiness, nausea, abdominal pain, diarrhea, vomiting, low platelet count, tremors, tiredness, and hair loss.
What does Depakote do to the brain?
What Depakote Does for the Brain. Divalproex sodium works by increasing the amount of gamma-aminobutyric acid (GABA) in the brain. The body produces GABA naturally. It is a chemical neurotransmitter — or brain messenger.
Is 1000 mg Depakote too much?
The recommended starting dose of Depakote for the prevention of migraine is 250 mg twice daily. The dose may be increased until migraine control is achieved. The maximum recommended dose is 1000 mg/day as needed.
What happens if Depakote doesn’t work?
If seizures continue, the doctor probably will change the amount of Depakote prescribed. If that doesn’t work, the next step may be either to prescribe a different seizure medicine by itself or to prescribe a combination of Depakote and another seizure medicine. Many are available.
What happens if Depakote levels are too high?
Increased ammonia levels. If this happens, you may get confused, disoriented, or have difficulty thinking.