Duloxetine is an antidepressant medicine. It’s used to treat depression and anxiety. It’s also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress urinary incontinence in women.
How much Cymbalta should I take for depression?
For treatment of depression: Adults—40 milligrams (mg) per day (given as 20 mg two times per day) to 60 mg per day (given either once a day or as 30 mg two times per day). Your doctor may increase your dose as needed. However, the dose is usually not more than 120 mg per day.
Is Duloxetine a strong antidepressant?
Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of long-term pain, but it’s more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.
Can Cymbalta make you more depressed?
Duloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.
What is the best time of day to take Cymbalta?
It is best to take duloxetine at the same time each day. Most people take it in the morning. If you find that you feel drowsy after taking it in the morning, try taking it in the evening.
Is 90 mg of duloxetine a lot?
Results from this study suggest that rapid dose escalation of duloxetine (60 mg/day –> 90 mg/day –> 120 mg/day) is safe and tolerable. Despite weekly escalation, the majority of adverse events were mild and transient and occurred in the first week of duloxetine dosing (at 60 mg once daily).
Why is Cymbalta bad for you?
Risks and Warnings. Cymbalta and other antidepressants may increase the risk for suicidal thoughts and behaviors in people under age 24. After you are prescribed Cymbalta, your doctor will monitor you closely for unusual behavior changes, new or worsening signs of depression, or suicidal thoughts.
How does Duloxetine make you feel?
Key facts. Duloxetine normally takes 2 to 4 weeks to work. It may take longer if you’re taking it for nerve pain. Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy.
Can I drink coffee with Cymbalta?
Caffeine may increase the blood levels and effects of DULoxetine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
How do you know Duloxetine is working?
How Long Does It Take For Duloxetine To Work? Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working.
Can Cymbalta make you crazy?
Some patients may feel worse instead of better when first starting drugs like Cymbalta or when changing the dose. You may feel more anxious, agitated, hostile, aggressive, impulsive, and feel like you are not yourself or become less inhibited. You may have thoughts of suicide, hurting yourself or other people.
Is 30 mg of Cymbalta effective?
For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to CYMBALTA before increasing to 60 mg once daily. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits.
Is Cymbalta a mood stabilizer?
As an SNRI, duloxetine inhibits the reuptake of the neurotransmitters serotonin and norepinephrine in the central nervous system and as a result, increasing the amounts available in the brain. These brain chemicals work to help regulate mood, so increasing their levels can help relieve symptoms of depression.
What should you not take with Cymbalta?
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.
How good is Cymbalta?
Cymbalta has an average rating of 6.3 out of 10 from a total of 538 ratings for the treatment of Depression. 52% of users who reviewed this medication reported a positive effect, while 29% reported a negative effect.
Will I lose weight on Cymbalta?
As with the 2006 analysis, the researchers found that in the short-term, those taking Cymbalta experienced modest weight loss, on average, compared with those taking placebo. In the longer-term, Cymbalta caused modest weight loss in some trials but modest weight gain in others.