Can trazodone cause central sleep apnea?

First, trazodone may lead to reduced arousals, which themselves may be destabilizing for control of breathing (9, 32). The ventilatory response to arousal may lead to marked CO2 fluctuations, which can lead to obstructive or central apnea depending on the prevailing pharyngeal mechanics.

Does Trazodone affect your breathing?

Trazodone can cause a severe allergic reaction. Symptoms can include: trouble breathing.

What medications cause central sleep apnea?

Cheyne-Stokes breathing is common in people who’ve had heart failure or a stroke. It happens in about half of central sleep apnea cases. Narcotic-induced central sleep apnea. Opioid medications like morphine, oxycodone, and codeine can affect your breathing patterns.

Does Trazodone affect oxygen levels?

Measurements and Main Results: Compared with placebo, trazodone resulted in a significant reduction in AHI (38.7 vs. 28.5 events/h, P = 0.041), without worsening oxygen saturation or respiratory event duration. Trazodone was not associated with a significant change in the non-REM arousal threshold (−20.3 vs.

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Is trazodone contraindicated for sleep apnea?

Despite concerns that the central nervous depressant effects may reduce upper airway muscle activity and worsen OSA, several carefully conducted studies have shown that common hypnotics such as trazodone, temazepam, zopiclone, and zolpidem do not systematically impair upper airway muscle activity during sleep.

Is it OK to take Trazodone every night?

Is it safe to take it for a long time? Yes, trazodone is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months, or even years. Some people need to take trazodone long term to treat depression or anxiety that keeps coming back.

Is Trazadone safe with sleep apnea?

Conclusions: These findings suggest that trazodone could be effective therapy for patients with OSA without worsening hypoxemia. Future studies should focus on underlying mechanisms and combination therapies to eliminate OSA.

What does Central sleep apnea feel like?

What Are the Symptoms of Central Sleep Apnea? Most people with central sleep apnea present with disturbed sleep, such as excessive daytime sleepiness, fragmented sleep, waking up feeling unrefreshed, or having morning headaches.

What can be done for central sleep apnea?

Treatments for central sleep apnea may include:

  • Addressing associated medical problems. …
  • Reduction of opioid medications. …
  • Continuous positive airway pressure (CPAP). …
  • Adaptive servo-ventilation (ASV). …
  • Bilevel positive airway pressure (BPAP). …
  • Supplemental oxygen. …
  • Medications.


How do you treat central sleep apnea naturally?

Sleep apnea lifestyle remedies

  1. Maintain a healthy weight. Doctors commonly recommend people with sleep apnea to lose weight. …
  2. Try yoga. Regular exercise can increase your energy level, strengthen your heart, and improve sleep apnea. …
  3. Alter your sleep position. …
  4. Use a humidifier. …
  5. Avoid alcohol and smoking. …
  6. Use oral appliances.
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What are the long term side effects of trazodone?

Trazodone Long Term Side Effects

  • Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, unsteadiness, increased fall risk).
  • Serotonin syndrome.
  • Confusion.
  • Angle-closure glaucoma.
  • Blurred vision.
  • Hypotension.
  • Fainting.


Is it OK to take 100mg of trazodone for sleep?

Trazodone is most often prescribed at doses between 25mg to 100mg as a sleep aid. However, studies show lower dosages of trazodone are effective and may cause less daytime sleepiness and fewer side effects because the drug is short acting.

How long do you sleep on trazodone?

The 3 to 6 hour half-life of trazodone makes it most suitable for treating sleep onset insomnia or maintenance insomnia. Trazodone as a sleep aid has several core benefits: Scientifically proven to effectively treat both primary insomnia and secondary insomnia. Trazodone can be used to treat sleep issues at low doses.

Can you take muscle relaxers with sleep apnea?

Commonly found in medications for pain., anxiety, and for sleeping, drugs with muscle relaxants tend to worsen obstructive sleep apnea as well as enhance side effects, such as even louder snoring. The back of the throat is already too relaxed with sleep apnea, as it makes air difficult to get through during sleep.

How does trazodone affect sleep apnea?

Conclusions: Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold without major impairment in dilator muscle activity or upper airway collapsibility.

Why is trazodone not helping me sleep?

Because of the chemical composition of trazodone, it has been found to have mild sedating effects, and it is less effective than other antidepressants for the treatment of depression. Therefore, trazodone has found greater utility as a sleep aid than it has as an antidepressant medication. You are not alone.

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