Acute hepatitis secondary to sertraline is a rare entity with very few reported cases so far. In our patient, the biochemical abnormalities and histopathological results, in relation to the drug history, suggests sertraline-induced hepatitis as the likely cause of hepatitis.
Does sertraline affect your liver?
Sertraline therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.
What antidepressants can cause liver damage?
Some antidepressants can damage your liver over time, including monoamine oxidase (MAO) inhibitors, tricyclic or tetracyclic antidepressants, bupropion, duloxetine and agomelatine. Antidepressant drugs with a lower risk of liver damage include citalopram, escitalopram, paroxetine and fluvoxamine.
Do antidepressants cause liver problems?
All antidepressants can induce hepatotoxicity, especially in elderly patients and those with polypharmacy. Liver damage is in most cases idiosyncratic and unpredictable, and it is generally unrelated to drug dosage.
Are there any long term side effects of sertraline?
To date, there are no known problems associated with long term use of sertraline. It is a safe and effective medication when used as directed.
Is sertraline a strong antidepressant?
Zoloft (sertraline) is a good and safe antidepressant that is also used to treat other psychiatric disorders such as panic disorder, post-traumatic stress disorder and obsessive compulsive disorder.
Why should you not take sertraline on a night?
Many people who experience nausea and other side effects from sertraline opt to take it at night in order to limit these side effects. Since sertraline can interfere with sleep in a small percentage of users, many people also opt to take sertraline in the morning.
What can I drink to flush my liver?
How Do You Flush Out Your Liver?
- Flush out with plenty of water intake: Water is the best flushing agent. …
- Get regular exercise: Exercise helps to burn extra calories that reduce your risk of diabetes, excess weight, high blood pressure, and high blood fat.
What’s the best natural antidepressant?
- SAM-e. S-adenosylmethionine (SAM-e) naturally occurs in the body. …
- St. John’s Wort. …
- Omega-3 fatty acids. Some types of fatty fish, such as tuna and albacore, contain omega-3 fatty acids. …
- Lavender. …
- 5-HTP. …
What medications should be avoided with liver disease?
The 10 Worst Medications for Your Liver
- 1) Acetaminophen (Tylenol) …
- 2) Amoxicillin/clavulanate (Augmentin) …
- 3) Diclofenac (Voltaren, Cambia) …
- 4) Amiodarone (Cordarone, Pacerone) …
- 5) Allopurinol (Zyloprim) …
- 6) Anti-seizure medications. …
- 7) Isoniazid. …
- Azathioprine (Imuran)
How long does it take for liver enzymes to return to normal?
With acute Hepatitis, AST levels usually stay high for about 1-2 months but can take as long as 3-6 months to return to normal.
What is the safest antidepressant?
Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest .
What happens if you drink alcohol with sertraline?
Mixing Zoloft with alcohol can exacerbate the symptoms of an upset stomach, possibly resulting in vomiting. Alcohol is a central nervous system depressant that by itself can cause depression. The consumption of alcohol can also worsen the symptoms of depression and make Zoloft less effective in treating these symptoms.
Can sertraline cause bad wind?
Common side effects of sertraline
Sexual problems such as decreased sex drive or erectile dysfunction Feeling sleepy or tired. Disturbances of the gut such as nausea, vomiting, diarrhoea, indigestion, wind, constipation, abdominal pain.
Do antidepressants shorten your life?
The analysis found that in the general population, those taking antidepressants had a 33 percent higher risk of dying prematurely than people who were not taking the drugs. Additionally, antidepressant users were 14 percent more likely to have an adverse cardiovascular event, such as a stroke or a heart attack.
Why is sertraline making me so tired?
Fatigue and tiredness are two of the most common side effects of sertraline, as well as several other SSRIs. If you’re using sertraline to treat depression, fatigue and tiredness from the medication can also be compounded by the effects of depression on your mood.