The diet drug “fen-phen.” Although the appetite suppressant “fen-phen” (dexfenfluramine and phentermine) has been taken off the market, former fen-phen users have a 23-fold increase risk of developing pulmonary hypertension, possibly years later. Liver diseases, rheumatic disorders, lung conditions.
How long does it take for phentermine to cause pulmonary hypertension?
The current Physician’s Desk Reference (PDR) guideline allows phentermine for a duration of 3-6 weeks; however, in our case, the patient had developed PAH with 5 weeks of medication.
Can phentermine cause lung problems?
Important warnings. Primary pulmonary hypertension (PPH) warning: This drug can cause PPH. This is a rare lung disease that may be fatal (cause death).
What medications can cause pulmonary hypertension?
Agents affecting serotonin metabolism (and related anorexigens): Anorexigens, such as aminorex, fenfluramine, benfluorex, phenylpropanolamine, and dexfenfluramine were the first class of medications recognized to cause pulmonary arterial hypertension.
What is the most common cause of pulmonary hypertension?
In the United States, the most common cause of pulmonary hypertension is left heart disease. Other conditions that can cause pulmonary hypertension include sickle cell disease; pulmonary embolus, which is a type of venous thromboembolism; and chronic obstructive pulmonary disease (COPD).
Is phentermine a speed?
There is a potential for misuse with phentermine, which is why it is a scheduled drug. It works in a similar way to amphetamines (like methamphetamine or “speed”) and cocaine, which are drugs that people use illegally and recreationally.
What should you not take with phentermine?
Do not use phentermine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Does phentermine affect your brain?
Summary: Users of widely prescribed diet pills may suffer irreversible loss of brain serotonin nerve terminals, possibly resulting in symptoms of anxiety, depression, cognitive and sleep problems, suggests the first author of a newly published report on fenfluramine side effects.
Can you take 2 phentermine a day?
Do not take two doses at one time. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phentermine can be fatal.
Can phentermine cause weight gain?
If you find yourself gaining weight while taking phentermine see your doctor. Phentermine should be used alongside dietary changes, exercise, and behavioral modification as discussed with your doctor.
How do you know when pulmonary hypertension is getting worse?
Often, shortness of breath or lightheadedness during activity is the first symptom. As the disease gets worse, symptoms can include the following: Increased shortness of breath, with or without activity. Fatigue (tiredness)
Does walking help pulmonary hypertension?
Some exercises are better for you if you have PAH. Good choices include: Light aerobic activity, like walking or swimming.
How do you fix pulmonary hypertension?
Treatments for pulmonary arterial hypertension
- anticoagulant medicines – such as warfarin to help prevent blood clots.
- diuretics (water tablets) – to remove excess fluid from the body caused by heart failure.
- oxygen treatment – this involves inhaling air that contains a higher concentration of oxygen than normal.
What worsens pulmonary hypertension?
Pulmonary hypertension is a form of high blood pressure that occurs in the lungs. It can be triggered by a variety of factors, including sleep apnea and chronic obstructive pulmonary disease or COPD, as it’s commonly called.
Should I worry about mild pulmonary hypertension?
Do not worry. Your cardiologist is correct. You do not need treatment for pulmonary hypertension.
What are the stages of pulmonary hypertension?
Stages of pulmonary arterial hypertension
- Class 1. The condition doesn’t limit your physical activity. …
- Class 2. The condition slightly limits your physical activity. …
- Class 3. The condition significantly limits your physical activity. …
- Class 4. You’re unable to carry out any type of physical activity without symptoms.