If you have had depression more than once, your doctor may recommend carrying on with trazodone for much longer. Is it safe to take it for a long time? Yes, trazodone is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months, or even years.
Is trazodone safe long term?
As far as is known, trazodone is safe for long-term use. Some people with severe or chronic depression or insomnia may use trazodone for extended periods.
What are the long term side effects of trazodone?
Trazodone Long Term Side Effects
- Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, unsteadiness, increased fall risk).
- Serotonin syndrome.
- Angle-closure glaucoma.
- Blurred vision.
Can Trazodone be taken as needed?
When prescribed for sleep, trazodone can be taken as a 50 mg to 100 mg dose at bedtime. If needed, the dose can be increased to up to 200 mg at bedtime to help with sleep. Those with both depression and sleep problems may need a higher dose in some cases — up to 300 mg at bedtime.
What are the dangers of trazodone?
Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- bad taste in mouth.
- changes in appetite or weight.
- weakness or tiredness.
Is it OK to take Trazodone every night?
Is it safe to take it for a long time? Yes, trazodone is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months, or even years. Some people need to take trazodone long term to treat depression or anxiety that keeps coming back.
Does Trazodone feel like Xanax?
Xanax is similar to trazodone in that it may cause side effects such as feeling tired and drowsy. When this occurs during the day, it can affect your day-to-day activities. However, unlike trazodone, Xanax and other benzodiazepine drugs can be addictive, even if you’ve been using them as directed.
What medications should not be taken with Trazodone?
Drugs you should not use with trazodone
Examples of these drugs include: Monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, tranylcypromine, or selegiline. You shouldn’t take trazodone with MAOIs or within 14 days of taking them. Taking these drugs together raises your risk for serotonin syndrome.
Can trazodone affect memory?
Trazodone produced small but significant impairments of short-term memory, verbal learning, equilibrium, and arm muscle endurance across time points.
How long do you sleep on trazodone?
The 3 to 6 hour half-life of trazodone makes it most suitable for treating sleep onset insomnia or maintenance insomnia. Trazodone as a sleep aid has several core benefits: Scientifically proven to effectively treat both primary insomnia and secondary insomnia. Trazodone can be used to treat sleep issues at low doses.
Does Trazodone work right away for sleep?
A handful of studies have shown that trazodone may improve sleep during the first two weeks of treatment. But the drug hasn’t been well-studied for longer than six weeks for people whose primary problem is insomnia.
How does trazodone make you feel?
Even at lower doses, trazodone can cause you to feel relaxed, tired, and sleepy. It does this by blocking chemicals in the brain that interact with serotonin and other neurotransmitters, such as, 5-HT2A, alpha1 adrenergic receptors, and H1 histamine receptors.
What is better than Trazodone for sleep?
Both drugs were tolerated well with few side effects. Both trazodone and Ambien helped people in the study sleep better during the first week, but only Ambien helped people sleep better the second week. The study found Ambien to be more effective than trazodone.
Can you just stop taking Trazodone?
Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor’s advice.
What drugs interact with Trazodone?
Severe Interactions of Trazodone include:
- arsenic trioxide.
Does Trazodone cause dementia?
The incidence of dementia in people prescribed trazodone was higher than in matched antidepressant users (1.8 versus 1.1 per 100 person-years), with a hazard ratio (HR) of 1.80 (95% confidence interval [CI] 1.56–2.09).