Phentermine, especially when combined with fenfluramine, has been associated with high pressures in the pulmonary arteries (pulmonary hypertension) and defects in heart valves, both serious complications. Physical and psychological dependence may occur with the long-term use of phentermine.
How long can you take phentermine safely?
Take phentermine exactly as directed. Most people takephentermine for 3 to 6 weeks; the length of treatment depends on how you respond to the medication. Phentermine can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period than your doctor tells you to.
Can phentermine cause health problems?
These include stroke, arrhythmia (irregular heartbeat), heart failure, coronary artery disease, valve disease, and uncontrolled high blood pressure. Phentermine may cause a serious increase in your blood pressure. This may make your heart work harder. The extra stress on your heart may make your heart disease worse.
What does phentermine do to your brain?
While the exact mechanisms behind the appetite-reducing effects of phentermine remain unclear, the drug is thought to act by increasing neurotransmitter levels in your brain ( 6 , 7 ). Neurotransmitters are your body’s chemical messengers and include norepinephrine, serotonin, and dopamine.
What happens if you take phentermine for years?
The researchers found that at 24 months, longer-term users of phentermine had more weight loss, with patients using continuously for >12 months losing 7.4 percent more than those who used for no more than three months.
Has phentermine killed anyone?
Forty-one (0.3 percent) of 13,972 phentermine users experienced a major adverse event (36 cardiovascular events; 5 deaths), but none of these was among the long-term users.
Should you take a break from phentermine?
After the tablet has melted, swallow or take a sip of water. Swallow the tablet whole. Do not crush, break, or chew it. Carefully follow your doctor’s instructions for a reduced-calorie diet plan and regular exercise.
Can phentermine cause liver damage?
No instances of acute liver failure or chronic liver injury have been linked to phentermine/topiramate, but it has had limited general clinical use. References on the hepatotoxicity and safety of phentermine and topiramate separately are given in the sections on the individual agents.
Can phentermine cause heart valve damage?
Exposure to the anorectic drug fenfluramine, alone or in combination with phentermine, a noradrenergic central nervous system stimulant, has been associated with unusual cardiac valvular morphology and resultant regurgitation of the left- and right-sided heart valves.
Can you stay on phentermine long term?
The authors concluded that phentermine is safe and effective for longer-term use—that is, >3 months—for weight loss in low-risk individuals.
Can phentermine change your personality?
Like many other sympathomimetics, phentermine is known to induce psychotic symptoms. Thus, phentermine associated psychotic symptoms have been reported repeatedly since 1960s. 10) Once the medications are stopped, psychotic symptoms generally improve in patients who had no prior history of psychotic disorder.
What happens when you stop taking phentermine?
Behavioural symptoms can also occur during diet pill withdrawal. You may not seem like yourself after you abruptly stop taking the pills. You may experience nervousness, anxiety and irritability. Depression can also set in, accompanied by fatigue and insomnia.
Can phentermine cause weight gain?
If you find yourself gaining weight while taking phentermine see your doctor. Phentermine should be used alongside dietary changes, exercise, and behavioral modification as discussed with your doctor.
Can you stop phentermine cold turkey?
Abrupt cessation of long-term phentermine therapy does not induce amphetamine-like withdrawal. Long-term phentermine therapy does not induce phentermine cravings. Symptoms observed after abrupt phentermine cessation represent loss of therapeutic effect and are not withdrawal.
Can you take phentermine every other day and still lose weight?
We suggest for those women trying to lose 25 lbs or less, you start weaning off the phentermine after the second month. Take the pill every other day for two weeks, then every third day, until you are down to 1 pill a week (usually Sunday) then stop completely.
Is phentermine a speed?
There is a potential for misuse with phentermine, which is why it is a scheduled drug. It works in a similar way to amphetamines (like methamphetamine or “speed”) and cocaine, which are drugs that people use illegally and recreationally.